Men Losing Y Chromosome With Age May Face Serious Health Risks

Research reveals that aging men progressively lose the Y chromosome in increasing numbers of their cells, a phenomenon previously thought to be benign but now linked to serious health complications. This chromosomal loss has been associated with heart disease, cancer, Alzheimer's disease, and reduced lifespan. Scientists theorize that cells lacking the Y chromosome may proliferate abnormally and disrupt essential body functions. Understanding this genetic mechanism could lead to new preventive strategies and treatments for age-related diseases in men. This discovery suggests that what was once considered a minor genetic quirk may actually be a significant contributor to age-related illness.

Originally published on
ScienceDaily Health
Read full article(opens in new tab)Fetched: March 21, 2026 at 10:11 AM



